Expression of autophagy-related protein beclin-1 in malignant canine mammary tumors

Expression of autophagy-related protein beclin-1 in malignant canine mammary tumors

BACKGROUND Autophagy is a self-catabolic mechanism that degrades unnecessary cellular components through lysosomal enzymes. Beclin-1, an autophagy-related protein, establishes the first connection between autophagy and tumorigenesis. The purpose of this study is to assess the Beclin-1 expression pattern and to determine its prognostic significance in patients with malignant canine mammary tumor...

Classification and grading of canine malignant mammary tumors

Histological grading is a good parameter to stratify tumors according to their biological aggressiveness. The Elston and Ellis grading method in humans, invasive ductal breast carcinomas and other invasive tumors are routinely used. The aims of this study were classification of mammary gland tumors and also application of a human grading method in canine mammary carcinoma. The samples included ...

classification and grading of canine malignant mammary tumors

histological grading is a good parameter to stratify tumors according to their biological aggressiveness. the elston and ellis grading method in humans, invasive ductal breast carcinomas and other invasive tumors are routinely used. the aims of this study were classification of mammary gland tumors and also application of a human grading method in canine mammary carcinoma. the samples included ...

The Expression of The Autophagy Gene Beclin-1 mRNA and Protein in Ectopic and Eutopic Endometrium of Patients with Endometriosis

Evaluation of c-KIT protein expression in canine mammary tumors

Background c-KIT is a proto-oncogene that synthesizes a tyrosine kinase protein responsible for cell growth. Higher expression of c-KIT protein in women normal breasts correlates with differentiation status of normal breast epithelium, while loss of c-KIT expression is observed during progression or malignant transformation of mammary epithelium. In bitches the role of this tyrosine kinase rece...